Read On the Production and Suppression of Muscular Twitchings and Hypersensitiveness of the Skin by Electrolytes (Classic Reprint) by Jacques Loeb Free Online
Book Title: On the Production and Suppression of Muscular Twitchings and Hypersensitiveness of the Skin by Electrolytes (Classic Reprint)|
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The author of the book: Jacques Loeb
Edition: Forgotten Books
Date of issue: February 5th 2018
ISBN 13: 9781332092291
Format files: PDF
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Excerpt from On the Production and Suppression of Muscular Twitchings and Hypersensitiveness of the Skin by Electrolytes
To test this idea further, Mr. W. E. Garrey and I undertook, in 1899, a series of experiments, not yet published, on the behavior of muscles in solutions of sodium salts whose anions precipitate calcium. The muscle itself contains calcium Salts, and we considered it likely that these calcium salts might help in preventing contractions. We therefore thought that by putting the muscle into solutions of sodium salts, which, by entering the muscle, precipitate the calcium contained In it, we might produce still more powerful rhythmical contractions than In a pure sodium chloride solution. This was found to be true. In Solutions Of sodium ﬂuoride, -oxalate, -carbonate, -phos phate, etc., of the proper concentration (1 gram-molecule in 8 liters of the solution), we Obtained similar, but more powerful, rhythmical contractions than in sodium.
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Read information about the authorJacques Loeb (April 7, 1859 – February 11, 1924) was a German-born American physiologist and biologist.
Loeb was educated at the universities of Berlin, Munich, and Strasburg (M.D. 1884). He took postgraduate courses at the universities of Strasburg and Berlin, and in 1886 became assistant at the physiological institute of the University of Würzburg, remaining there till 1888. In a similar capacity, he then went to Strasburg University. During his vacations he pursued biological researches, at Kiel in 1888, and at Naples in 1889 and 1890.
In 1892 he was called to the University of Chicago as assistant professor of physiology and experimental biology, becoming associate professor in 1895, and professor of physiology in 1899. John B. Watson (the "father of Behaviorism") was a student of Loebs neurology classes at University of Chicago. In 1902 he was called to fill a similar chair at the University of California.
In 1910 Loeb moved to the Rockefeller Institute for Medical Research in New York, where he headed a department created for him. He remained at Rockefeller (now Rockefeller University) until his death. Throughout most of these years Loeb spent his summers at the Marine Biological Laboratory in Woods Hole, Massachusetts, performing experiments on various marine invertebrates. It was there that Jacques Loeb performed his most famous experiment, on artificial parthenogenesis. Loeb was able to cause the eggs of sea urchins to begin embryonic development without sperm. This was achieved by slight chemical modifications of the water in which the eggs were kept, which served as the stimulus for the development to begin.
Loeb became one of the most famous scientists in America, widely covered in newspapers and magazines. He was the model for the character of Max Gottlieb in Sinclair Lewis's Pulitzer-winning novel Arrowsmith, the first great work of fiction to idealize and idolize pure science. Mark Twain also wrote an essay titled "Dr. Loeb's Incredible Discovery", which urges the reader not to support a rigid general consensus, but instead be open to new scientific advances.
Loeb was nominated many times for the Nobel Prize but never won.
His younger brother Leo also emigrated to the United States where he became a noted pathologist.
The main subjects of Loeb's work were:
Animal tropisms and their relation to the instincts of animals
Heteromorphosis, the replacement of an injured or removed organ by a different organ
Toxic and antitoxic effects of ions
Hybridization of the eggs of sea-urchins by the sperm of starfish